ab24480Anti-HE4 antibody

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Anti-HE4 antibodyDescriptionRabbit polyclonal to HE4Tested applicationsWB, IHC-P

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Anti-HE4 antibody

Description

Rabbit polyclonal to HE4

Tested applications

WB, IHC-Pmore details

Cross reactivity

Anti-HE4 antibody

Reacts with

Human

Immunogen

Human mature HE4 fused to glutathione S-transferase. Produced in E.coli.

Positive control

Normal human epididymis or human ovarian tumour.

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.1% Sodium AzideConstituents: PBS, BSA

Concentration

  • 100 µl at 0.03mg/ml

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Tags & Cell Markers >> Cell Type Markers >> Tumor Associated

  • Datasheet PDF
  • SDS
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - HE4 antibody (ab24480)(enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab24480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

    WB: 1/100. Detects a ban...Read more →

    WB: 1/100. Detects a band of approximay 25 kDa (predicted molecular weight: 13 kDa).

  • ShowHide1 Image

    IHC-P

    IHC-P: 1/40. Perform hea...Read more →

    IHC-P: 1/40. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

Tissue specificity

Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.

Sequence similarities

Contains 2 WAP domains.

Cellular localization

Secreted.

Target information above from: UniProt accessionQ14508The UniProt ConsortiumThe Universal Protein Resource (UniProt) in 2010Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Form

There are 5 isoforms produced by alternative splicing.

Alternative names

  • dJ461P17.6 antibody
  • EDDM4 antibody
  • epididymal protein 4 antibody
  • Epididymal secretory protein E4 antibody
  • Epididymis specific whey acidic protein type four disulfide core antibody
  • HE 4 antibody
  • Major epididymis specific protein E4 antibody
  • Major epididymis-specific protein E4 antibody
  • MGC57529 antibody
  • Putative protease inhibitor WAP5 antibody
  • WAP 5 antibody
  • WAP domain containing protein HE4 antibody
  • WAP four disulfide core domain 2 antibody
  • WAP four disulfide core domain protein 2 antibody
  • WAP four-disulfide core domain protein 2 antibody
  • WAP5 antibody
  • WFDC 2 antibody
  • WFDC2 antibody
  • WFDC2_HUMAN antibody

see all

Database links

  • Entrez Gene: 10406 Human
  • SwissProt: Q14508 Human
  • Unigene: 2719 Human

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