Applications

FA

Synonyms:

Bocatriol, Calcijex, Decostriol, Osteotriol, Rocaltrol, Tirocal, D3, 1,25-Dihydroxyvitamin

Formulation:

Crystalline solid

Chemical Name:

(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

Molecular Formula:

C₂₇H₄₄O₃

Molecular Weight:

416.6

CAS Number

32222-06-3

Purity:

≥97%

Storage Conditions:

Product should be kept at -20°C.

References:

Rigby, W. F., Stacy, T., & Fanger, M. W. (1984). Inhibition of T lymphocyte mitogenesis by 1, 25-dihydroxyvitamin D3 (calcitriol).Journal of Clinical Investigation,74(4), 1451.

Gross, C., Stamey, T., Hancock, S., & Feldman, D. (1998). Treatment of early recurrent prostate cancer with 1, 25-dihydroxyvitamin D3 (calcitriol).The Journal of urology,159(6), 2035-2040.

Daniel, C., Sartory, N. A., Zahn, N., Radeke, H. H., & Stein, J. M. (2008). Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile.Journal of Pharmacology and Experimental Therapeutics,324(1), 23-33.