Recombinant Murine Amphiregulin

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Recombinant Murine Amphiregulin

货号:315-36-10,315-36-100,315-36-1000,315-36-250,315-36-50,315-36-500

规格:10ug,100ug,1mg,250ug,50ug,500ug

价格:640,3505,14066,6139,1560,9121

产品类型:细胞因子添加物

品牌:PeproTech

产品描述:Amphiregulin is an EGF-related growth factor that signals through the EGF/TGF-α receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant Murine Amphiregulin is an 11.3 kDa glycoprotein consisting of 98 amino acid residues.来源:E.coli别名:AR, AREG, Colorectum cell-derived growth factor (CRDGF)氨基酸序列:SVRVEQVIKP KKNKTEGEKS TEKPKRKKKG GKNGKGRRNK KKKNPCTAKF QNFCIHGECR YIENLEVVTC NCHQDYFGER CGEKSMKTHS EDDKDLSK纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expectedED50for this effect is 5-10 ng/ml.Calculated Molecular Weight:11.5 kDaAccession Number:P31955Gene ID:11839交叉反应:Mouse原产地:USA仅用于科研,不能用于临床和诊断。

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