Animal-Free Recombinant Human IL-17 (IL-17A)
货号：AF-200-17-5,AF-200-17-25,AF-200-17-100,AF-200-17-250,AF-200-17-500,AF-200-17-1000
规格：5ug,25ug,100ug,250ug,500ug,1mg
价格：1250,2830,50820,22230,33030,50820
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：AF-200-17产品描述：The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains that are secreted by activated T-cells, which act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant Human IL-17A is a 31.3 kDa, disulfide-linked homodimer of two 137 amino acid, polypeptide chains.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:IL-17, CTLA-8AA Sequence (monomer):MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVAPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Measured by its ability to induce IL-6 production by NHDF cells using a concentration range of 0.5-1.5 ng/ml.Calculated Molecular Weight:31.3 kDaAccession Number:Q16552Gene ID:3605crossreactivity:Cow,HumanCountry Of Origin:USANot for human use. |
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