Animal-Free Recombinant Human IL-17E
货号:AF-200-24-5,AF-200-24-25,AF-200-24-100,AF-200-24-250,AF-200-24-500,AF-200-24-1000
规格:5ug,25ug,100ug,250ug,500ug,1mg
价格:1250,2830,12700,22230,33030,50802
产品类型:细胞因子添加物
品牌:PeproTech
| 产品详情产品编号:AF-200-24产品描述:IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulates secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant Human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 146 amino acid polypeptide chains.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:Interleukin-17E, IL-25AA Sequence (monomer):MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT HKGYCLERRL YRVSLACVCV RPRVMGPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100 ng/ml.Note: Results may vary with PBMC donors.Calculated Molecular Weight:33.8 kDaAccession Number:Q9H293Gene ID:64806Country Of Origin:USANot for human use. |