Recombinant Murine IL-1α
货号:211-11A-10,211-11A-100,211-11A-1000,211-11A-2,211-11A-250,211-11A-50,211-11A-500
规格:10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格:1418,8297,33241,582,14522,4977,21570
产品类型:细胞因子添加物
品牌:PeproTech
| 产品描述:IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Murine IL-1α is a 17.9 kDa protein containing 156 amino acid residues.来源:E.coli别名:Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)氨基酸序列:SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 108units/mg.Calculated Molecular Weight:17.9 kDaAccession Number:P01582Gene ID:16175交叉反应:Human,Mouse,Mouse + Chicken原产国:USA |