Recombinant Murine TNF-α
货号：315-01A-100,315-01A-1000,315-01A-20,315-01A-250,315-01A-5,315-01A-50,315-01A-500
规格：100ug,1mg,20ug,250ug,5ug,50ug,500ug
价格：6379,25574,1418,11161,582,3831,16588
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant Murine TNF-α is a soluble 156 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.来源:E.coli别名:Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin氨基酸序列:MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the cytolysis of murine L929 cells in the presence of actinomycin D is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107units/mg.Calculated Molecular Weight:17.3 kDaAccession Number:P06804Gene ID:21926交叉反应:Cow,Human,Human + Hamster,Monkey,Mouse,Mouse + Bacteria,Mouse + Human,Rat原产地:USA仅用于科研，不能用于临床和诊断。 |
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