Animal-Free Recombinant Human Artemin
货号：AF-450-17-5,AF-450-17-20,AF-450-17-50,AF-450-17-100,AF-450-17-250,AF-450-17-500,AF-450-17-1000
规格：5ug,20ug,50ug,100ug,250ug,500ug,1mg
价格：1250,2830,7620,12700,22230,33030,50820
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRα (α1-α4) receptors. Artemin prefers the receptor GFRα3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia, such as sympathetic, neural crest and placodally-derived sensory neurons, and dopaminergic midbrain neurons. The functional human Artemin ligand is a disulfide-linked homodimer of two 12.0 kDa polypeptide monomers. Each monomer contains seven conserved cysteine residues, one of which is used for interchain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine-knot configuration.Recombinant Human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits.Manufactured using all Animal-Free reagents.来源:E.coli别名:ART, ARTN, Enovin, Neublastin氨基酸序列:AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Not available.Calculated Molecular Weight:24.2 kDaAccession Number:Q5T4W7Gene ID:9048原产国:USA |
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