Recombinant Human IFN-β
货号：300-02BC-100,300-02BC-1000,300-02BC-20,300-02BC-250,300-02BC-5,300-02BC-50,300-02BC-500
规格：100ug,1mg,20ug,250ug,5ug,50ug,500ug
价格：8297,33241,1418,15422,582,4977,21570
产品类型：细胞因子添加物
品牌：PeproTech
产品描述: Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. PeproTech’s Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFN-β has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry.*Human IFN-β(Catalog Number 300-02BC) has replaced Human IFN-β(Catalog Number 300-02B)别名:Fibroblast Interferon, IFNB1, Type I Interferon氨基酸序列:MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN来源:CHO cells纯度:Greater than 95% by SDS-PAGE gel and HPLC analyses.生物活性:Assay #1:Measured by its ability to induce apoptosis in HeLa cells. The expectedED50for this effect is 20-30 ng/ml.Assay #2:Determined by a cytotoxicity assay using human TF-1 cells. The expectedED50is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107units/mg.Calculated Molecular Weight:20 kDaAccession Number:P01574Gene ID:3456Note:1mg will be provided as 2x500μg.交叉反应:Monkey, Mouse, Human原产地:USA仅用于科研，不能用于临床和诊断。 |
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