Animal-Free Recombinant Human MIP-1α (CCL3)
货号：AF-300-08-5,AF-300-08-20,AF-300-08-100,AF-300-08-250,AF-300-08-500,AF-300-08-1000
规格：5µg,20ug,100ug,250ug,500ug,1mg
价格：1250,2830,12700,22230,33030,50820
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1α and MIP-1β exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes, and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant Human MIP-1α is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.Manufactured using all Animal-Free reagents.来源:E.coli别名:Macrophage Inflammatory Protein-1α, CCL3, LD78α氨基酸序列:ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSAPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.Calculated Molecular Weight:7.8 kDaAccession Number:P10147Gene ID:6348原产国:USA |
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