Animal-Free Recombinant Murine IL-4
货号：AF-214-14-5,AF-214-14-20,AF-214-14-50,AF-214-14-100,AF-214-14-250,AF-214-14-500,AF-214-14-1000
规格：5µg,20ug,50ug,100ug,250ug,500ug,1mg
价格：1250,2830,8080,13470,23570,35030,53900
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant Murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.Manufactured using all Animal-Free reagents.来源:E.coli别名:BCGF, BCDF, B cell stimulating factor (BSF-1)氨基酸序列:MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50was determined by the dose-dependent stimulation of the proliferation of murine HT-2 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105units/mgCalculated Molecular Weight:13.5 kDaAccession Number:P07750Gene ID:16189交叉反应:Mouse,Pig Intestinal Worm,Rat,Trout原产国:USA |
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