Animal-Free Recombinant Human /Murine/Rat Activin A (E.coli derived)
货号：AF-120-14E-2,AF-120-14E-10,AF-120-14E-50,AF-120-14E-100,AF-120-14E-250,AF-120-14E-500,AF-120-14E-1000
规格：2µg,10µg,50µg,100µg,250µg,500µg,1mg
价格：1250,2830,9930,16550,28960,43030,66220
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：AF-120-14E产品描述：Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:Inhibin beta-1, FRP, FSH (Follicle-stimulating hormone)-releasing protein, Erythroid Differentiation Factor (EDF)AA Sequence (monomer):GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCSPurity:≥ 97% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expectedED50is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105units/mg.Calculated Molecular Weight:26 kDaAccession Number:P08476Gene ID:3624Note:1mg will be provided as 2x500μg.crossreactivity:Chicken,Dog,Frog,Human,Human + Mouse,Mouse,RatCountry Of Origin:USANot for human use. |
QQ:1749072012