Recombinant Human BMP-4 (E.coli derived)
货号：120-05ET-2,120-05ET-250,120-05ET-50,120-05ET-500,120-05ET-10,120-05ET-100,120-05ET-1000
规格：2µg,250µg,50µg,500µg,10µg,100µg,1mg
价格：640,15974,5475,23727,1560,9290,36565
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：120-05ET产品描述：Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’sE.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa.Source:E.coliSynonyms:Bone Morphogenetic Protein-4, BMP-2B, DVR4AA Sequence (monomer):KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCRPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expectedED50for this effect is 5-10 ng/ml.Calculated Molecular Weight:23.9 kDaAccession Number:P12644Gene ID:652Note:1mg will be provided as 2x500μg.crossreactivity:Human,Mouse,Pig,RatCountry Of Origin:USANot for human use. |
| product.subtitle.recentcitations |
| 第一作者 | Herdenberg, C |
| 标题 | LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes. |
| 文献引用 | Communications Biology; 4(1) pg90PubMed Id |
| PubMed Id | 33469151 |
| 第一作者 | Padmashri, R |
| 标题 | Modeling Human-specific Interlaminar Astrocytes in the Mouse Cerebral Cortex. |
| 文献引用 | The Journal Of Comparative Neurology;PubMed Id |
| PubMed Id | 32639590 |
| 第一作者 | Li, N |
| 标题 | microRNA-181c-5p promotes the formation of insulin-producing cells from human induced pluripotent stem cells by targeting smad7 and TGIF2 |
| 文献引用 | Cell Death & Disease; 11(6) pg462PubMed Id |
| PubMed Id | 32541687 |
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