货号：300-02AA-1000

规格：1000µg

价格：9150

产品类型：细胞因子添加物

品牌：PeproTech

300-02AA

Leukocyte interferon, B cell interferon, Type I interferon

Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid stable molecule that signals through IFNα/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant human IFN-α is a 19.2 kDa protein containing 165 amino acid residues.

CDLPQTHSLG SRRTLMLLAQ MRKISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE

E.coli

Greater than 98% by SDS-PAGE gel and HPLC analyses.

The specific activity as determined in a viral resistance assay was found to be ≥ 1.8 x 10⁸units/mg.

Human

n/a

仅用于研究。不适用于诊断或治疗。