Anti-Mouse IFN gamma SAFIRE Purified

2024-10-15

Anti-Mouse IFN gamma SAFIRE Purified

货号:80822-25-25,80822-25-500

规格:25ug,500 ug

价格:1210,3520

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :80822-25

Description

The R4-6A2 monoclonal antibody specifically reacts with mouse interferon gamma (IFN-g), an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN gamma receptors are present in most immune cells, which respond to its signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. Additionally, it stimul

Additional Information

ates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.

Clone

R4-6A2

Format:

SAFIRE Purified

Applications

FA

Reactivity

Mouse

Isotype:

Rat IgG1, kappa

Research Interest:Innate Immunity,Adaptive Immunity
Cell Type:NK and NKT Cells,T Cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Spitalny, G. L., & Havell, E. A. (1984). Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities.The Journal of experimental medicine,159(5), 1560-1565.

Grau, G. E., Heremans, H., Piguet, P. F., Pointaire, P., Lambert, P. H., Billiau, A., & Vassalli, P. (1989). Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor.Proceedings of the National Academy of Sciences,86(14), 5572-5574.

Sadick, M. D., Heinzel, F. P., Holaday, B. J., Pu, R. T., Dawkins, R. S., & Locksley, R. M. (1990). Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.The Journal of experimental medicine,171(1), 115-127.

技术参数
© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://biorod.cn/thread-15476.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价