Clone

RORg2

Format:

Purified

Applications

FA

Reactivity

Mouse

Isotype:

Armenian hamster IgG

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Ruan, Q., Kameswaran, V., Zhang, Y., Zheng, S., Sun, J., Wang, J., ... & Chen, Y. H. (2011). The Th17 immune response is controlled by the Rel–RORγ–RORγT transcriptional axis.The Journal of experimental medicine,208(11), 2321-2333.

Jetten, A. M. (2009). Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism.Nucl Recept Signal,7(3).

He, Y. W., Deftos, M. L., Ojala, E. W., & Bevan, M. J. (1998). RORγt, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells.Immunity,9(6), 797-806.

Sun, Z., Unutmaz, D., Zou, Y. R., Sunshine, M. J., Pierani, A., Brenner-Morton, S., ... & Littman, D. R. (2000). Requirement for RORγ in thymocyte survival and lymphoid organ development.Science,288(5475), 2369-2373.