SC-1

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SC-1

货号:8393780-1,8393780-10

规格:1mg,10mg

价格:550,2750

产品类型:小分子化合物

品牌:Biogems

Description

Pluripotin is an inhibitor of both RasGAP and ERK1. The inhibition of RasGAP is used to promote self-renewal and the inhibition of ERK1 blocks cell differentiation. Pluripotin can be conbined with leukemia inhibitory factor (LIF) to promote the derivation of embryonic cell lines from refractory strains.

Additional Information

Applications

FA

Synonyms:

SC-1, SC1

Formulation:

Crystalline solid

Chemical Name:

N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide

Molecular Formula:

C27H25F3N8O2

Molecular Weight:

<div "class="productview-attribute-conten_div">550.5

CAS Number

839707-37-8

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Yang, W., Wei, W., Shi, C., Zhu, J., Ying, W., Shen, Y., ... & Deng, H. (2009). Pluripotin combined with leukemia inhibitory factor greatly promotes the derivation of embryonic stem cell lines from refractory strains.Stem Cells,27(2), 383-389.

Pieters, T., Haenebalcke, L., Hochepied, T., D’Hont, J., Haigh, J. J., Van Roy, F., & van Hengel, J. (2012). Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells.Stem Cell Reviews and Reports,8(3), 768-778.

Duan, H., Wang, Y., Yang, L., Qu, M., Wang, Q., Shi, W., & Zhou, Q. (2012). Pluripotin enhances the expansion of rabbit limbal epithelial stem/progenitor cells in vitro.Experimental eye research,100, 52-58.

技术参数
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