Applications

FA

Synonyms:

MLS001074886, SCHEMBL15565919, SMR000568408, 6BIO

Formulation:

Crystalline solid

Chemical Name:

(3E)-6-bromo-3-[3-(hydroxyamino)indol-2-ylidene]-1H-indol-2-one

Molecular Formula:

C₁₆H₁₀BrN₃O₂

Molecular Weight:

CAS Number

667463-62-9

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Meijer, L., Skaltsounis, A. L., Magiatis, P., Polychronopoulos, P., Knockaert, M., Leost, M., ... & Greengard, P. (2003). GSK-3-selective inhibitors derived from Tyrian purple indirubins.Chemistry & biology,10(12), 1255-1266.

Tseng, A. S., Engel, F. B., & Keating, M. T. (2006). The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes.Chemistry & biology,13(9), 957-963.

Sato, N., Meijer, L., Skaltsounis, L., Greengard, P., & Brivanlou, A. H. (2004). Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor.Nature medicine,10(1), 55-63.