Anti-Human CD107a (LAMP-1) Purified

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Anti-Human CD107a (LAMP-1) Purified

货号:19111-20-25,19111-20-100

规格:25 μg,100 μg

价格:660,1210

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :19111-20

Description

The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.

Additional Information

Clone

H4A3

Format:

Purified

Applications

FC, IHC, WB, IP

Reactivity

Human

Isotype:

Mouse IgG1, kappa

Research Interest:Innate Immunity
Cell Type:T Cells,Monocytes and Macrophages,NK and NKT Cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Chen, J. W., Cha, Y. I. N. G., Yuksel, K. U., Gracy, R. W., & August, J. T. (1988). Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens.Journal of Biological Chemistry,263(18), 8754-8758.

Grützkau, A., Smorodchenko, A., Lippert, U., Kirchhof, L., Artuc, M., & Henz, B. M. (2004). LAMP‐1 and LAMP‐2, but not LAMP‐3, are reliable markers for activation‐induced secretion of human mast cells.Cytometry Part A,61(1), 62-68.

Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J. J., Van den Brule, F., Castronovo, V., ... & Coninck, W. D. (1998). Expression of Lamp‐1 and Lamp‐2 and their interactions with galectin‐3 in human tumor cells.International journal of cancer,75(1), 105-111.

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