Anti-Human CD8a PE-Cy7
货号：10131-77 -25,10131-77 -100
规格：25 tests,100 tests
价格：801,2546
产品类型：流式抗体
品牌：Biogems
物种：人
宿主：小鼠
抗体亚型：IgG
荧光染料：Purified
Catalog Number :10131-77
Description
The RPA-T8 monoclonal antibody specifically reacts with the human CD8a molecule, a 32 kDa cell surface receptor expressed either as a heterodimer (CD8 α/β) or as a homodimer (CD8 α/α) on the majority of thymocytes, a subpopulation of mature T cells, and natural killer cells. CD8 interacts with the major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. The RPA-T8 antibody reacts with 13-48% of peripheral lymphocytes, 80% of thymocytes, and a subset of natural killer cells.
RPA-T8, OKT8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.
Additional Information
Clone | RPA-T8 |
Format: | PE-Cyanine7 |
Applications | FC |
Reactivity | Human |
Isotype: | Mouse IgG1, kappa |
| Research Interest: | Adaptive Immunity |
| Cell Type: | NK and NKT Cells,T Cells |
Preperation: | The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | Knapp W(1989)Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York |
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