Donkey anti-Goat IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 680/驴抗羊 IgG (H+L) 交叉吸附，Alexa Fluor 680

货号：A-21084

规格：500μl

价格：3625

产品类型：荧光二抗

品牌：Thermo Fisher

物种：山羊

宿主：驴

抗体亚型：IgG

荧光染料：Alexa Fluor 680

点击查看所有Alexa Fluor 荧光二抗

抗体类型:	荧光二抗	同型对照：	IgG
免疫原性：	Gamma Immunoglobins Heavy and Light chains	用法：	1-10 μg/mL (ICC)；1-10 μg/mL (IF)； 0.04-0.2 μg/mL (WB)

This secondary antibody is designed for fluorescent Western blot detection on various near-infrared fluorescence instruments. This antibody can be used for multi-color and multiplexing detection when using other antibodies conjugated to compatible Alexa Fluor™ dyes and wavelengths. Other applications of this antibody include immunofluorescent and fluorescent imaging applications when using instrumentation with appropriate excitation and detection capabilities.Background/Target InformationAnti-Goat secondary antibodies are affinity-purified antibodies with well-characterized specificity for goat immunoglobulins and are useful in the detection, sorting or purification of its specified target. Secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody. Most commonly, secondary antibodies are generated by immunizing the host animal with a pooled population of immunoglobulins from the target species and can be further purified and modified (i.e. immunoaffinity chromatography, antibody fragmentation, label conjugation, etc.) to generate highly specific reagents.

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参考文献：

1. PloS oneEvaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer risk."A21084 was used in western blot to define the effects of the Rad50 Interacting Protein 1 gene heterozygosity on tumorigenesis"AuthorsOtterpohl KL,Gould KA2. FASEB journal : official publication of the Federation of American Societies for Experimental BiologyRegulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells."A21084 was used in western blot to report that the receptor tyrosine kinase AXL is efficiently and sequentially cleaved by alpha- and beta-secretases in various types of cancer cell lines"AuthorsLu Y,Wan J,Yang Z,Lei X,Niu Q,Jiang L,Passtoors WM,Zang A,Fraering PC,Wu F3. OncotargetAndrogen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner."A21084 was used in western blot to define and study the androgen response element within the SEMA3C locus"AuthorsTam KJ,Dalal K,Hsing M,Cheng CW,Khosravi S,Yenki P,Tse C,Peacock JW,Sharma A,Chiang YT,Wang Y,Cherkasov A,Rennie PS,Gleave ME,Ong CJ4. Molecular and cellular proteomics : MCPAssembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress."A-21084 was used in western blot to characterize the response to electrophile stress by assembly stoichiometry and dynamics of the apoptosis signal-regulating kinase (ASK) signalosome"AuthorsFederspiel JD,Codreanu SG,Palubinsky AM,Winland AJ,Betanzos CM,McLaughlin B,Liebler DC5. Nature communicationsR function and expression with rapid antidepressant properties."A-21084 was used in western blot to investigate how acute ethanol exposure results in lasting antidepressant and anxiolytic behaviors"AuthorsWolfe SA,Workman ER,Heaney CF,Niere F,Namjoshi S,Cacheaux LP,Farris SP,Drew MR,Zemelman BV,Harris RA,Raab-Graham KF

技术参数

产品应用 ICC;IF;WB

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