1.Immunity HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33. "MA1-21316 was used in an ELISA assay to study how HpARI employs a novel molecular strategy to suppress type 2 immunity in both infection and allergy." AuthorsOsbourn M,Soares DC,Vacca F,Cohen ES,Scott IC,Gregory WF,Smyth DJ,Toivakka M,Kemter AM,le Bihan T,Wear M,Hoving D,Filbey KJ,Hewitson JP,Henderson H,Gonzàlez-Cìscar A,Errington C,Vermeren S,Astier AL,Wallace WA,Schwarze J,Ivens AC,Maizels RM,McSorley HJ 2.Scientific reports PHF20 positively regulates osteoblast differentiation via increasing the expression and activation of Runx2 with enrichment of H3K4me3. "MA1-21316 was used in Western Blotting to indicate that methyl lysine-binding protein PHF20 might be a novel regulator of osteoblast differentiation." AuthorsYang JW,Jeong BC,Park J,Koh JT 3.eLife The packing density of a supramolecular membrane protein cluster is controlled by cytoplasmic interactions. "MA1-21316 was used in Western Blotting to study the influence of a cytoplasmic protein domain on the clustering behaviour of syntaxin-molecules." AuthorsMerklinger E,Schloetel JG,Weber P,Batoulis H,Holz S,Karnowski N,Finke J,Lang T 4.The Journal of biological chemistry Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP. "MA121316 was used in western blot to demonstrate that cyclic adenosine monophosphate-dependent Rap1 signaling to extracellular signal-regulated kinases and Rap1 is potentiated by PKA due to sustained binding of B-Raf to Rap1" AuthorsTakahashi M,Li Y,Dillon TJ,Stork PJ 5.Scientific reports Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. "MA1-21316 was used in immunocytochemistry to elucidate how p21 is suppressed in embryonic stem cells" AuthorsItahana Y,Zhang J,Göke J,Vardy LA,Han R,Iwamoto K,Cukuroglu E,Robson P,Pouladi MA,Colman A,Itahana K |