SOX2 Monoclonal Antibody (10F10C9)

货号：MA5-15449

规格：100 µL

价格：4692

产品类型：流式抗体

品牌：Thermo Fisher

抗原：SOX2

物种：人

宿主：小鼠

抗体亚型：其它

克隆号：10F10C9

荧光染料：Purified

类型:	单抗	同型对照：	IgG1
免疫原性：	Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.	用法：	1/500 - 1/2000(WB)

Product Specific InformationMA5-15449 targets SOX2 in WB applications and shows reactivity with Human samples.The MA5-15449 immunogen is purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.MA5-15449 detects SOX2 which has a predicted molecular weight of approximately 34.3kDa.Target InformationSOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

数据

SOX2 Antibody (MA5-15449) in WBWestern blot analysis of SOX2 using a SOX2 monoclonal antibody (Product # MA5-15449) against a truncated Trx-SOX2 recombinant protein (1) and truncated MBP-SOX2 (aa1-170) recombinant protein (2).

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