Nkx2.5 Polyclonal Antibody
货号：PA5-23387
规格：100 µg
价格：4880
产品类型：免疫组化一抗
品牌：eBioscience
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
类型: | 多抗 | 同型对照： | |
浓度： | 0.5 mg/mL | 用法： | 5 µg/mL（IHC (P)）；1-2 µg/mL(WB) |
免疫原性： | Synthetic peptide (305 SPGIPQSNSGVSTLHG 320) of NKX2-5 protein |
靶标信息NKX2-5 is a transcription factor protein which plays a crucial role in cardiac development and differentiation. It is a low molecular weight protein of 35-38 kDa depending on phosphorylation status. Expression is mainly restricted to the heart. But during embryogenesis NKX2-5 expression has also been detected in spleen-precursor cells. Over expression of NKX2-5 resulted in expression of neuronal markers in C2C12 murine myogenic cells. Functionally it is involved in differentiation processes in heart development and in homeostasis and survival of cardiac myocytes as well maintains the initial muscle differentiation paradigm.
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| Nkx2.5 Antibody (PA5-23387) in IHC (P) Immunohistochemical analysis of NKX2-5 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and a NKX2-5 polyclonal antibody (Product # PA5-23387) (bottom left, right) at 5 µg/mL. Nkx2.5 Antibody (PA5-23387) in WB Western blot analysis of NKX2-5 in human heart lysate using 1) prebleed and 2) a NKX2-5 polyclonal antibody (Product # PA5-23387) at 1 µg/mL. |
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| 二抗荧光二抗免疫组化一抗标签抗体 |
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