Uracil N-Glycosylase / 尿嘧啶 N-糖基化酶

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Uracil N-Glycosylase / 尿嘧啶 N-糖基化酶

货号: UG131K

规格:1000 U

价格:18068

产品类型:PCR 及DNA聚合酶

品牌:Lucigen

Uracil N-Glycosylase (UNG) hydrolyzes the N-glycosidic bond between the deoxyribose sugar and uracil in DNA that contains deoxyuridine in place of thymidine.1 The enzyme is fully active at 37°C, 42°C, and 50°C. UNG is active on both single- and double-stranded DNA that contains uracil, but has no activity on RNA or 2′-deoxyuridine-5′-monophosphate. The enzyme does not have AP endonuclease activity. Uracil-containing DNA can be synthesized in vitro with various DNA polymerases in reactions that contain dUTP in place of dTTP.2 UNG is supplied with a dilution buffer for applications requiring lower concentrations of enzyme.
优点:
▪ Hydrolyzes the N-glycosidic bond between the deoxyribose sugar and uracil in DNA containing deoxyuridine in place of thymidine▪ Well-suited for use in DNA repair research studie
相关产品:
▪2´-Fluorine-dUTP(#R2F110U)
参考文献:
1. Lindahl, T. et al., (1977) J. Biol. Chem. 252, 3286. 2. Longo, M.C. et al., (1990) Gene 93, 125.

技术参数

产品优点 - Hydrolyzes the N-glycosidic bond between the deoxyribose sugar and uracil in DNA containing deoxyuridine in place of thymidine - Well-suited for use in DNA repair research studie

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