Uracil N-Glycosylase / 尿嘧啶 N-糖基化酶
货号: UG131K
规格:1000 U
价格:18068
产品类型:PCR 及DNA聚合酶
品牌:Lucigen
Uracil N-Glycosylase (UNG) hydrolyzes the N-glycosidic bond between the deoxyribose sugar and uracil in DNA that contains deoxyuridine in place of thymidine.1 The enzyme is fully active at 37°C, 42°C, and 50°C. UNG is active on both single- and double-stranded DNA that contains uracil, but has no activity on RNA or 2′-deoxyuridine-5′-monophosphate. The enzyme does not have AP endonuclease activity. Uracil-containing DNA can be synthesized in vitro with various DNA polymerases in reactions that contain dUTP in place of dTTP.2 UNG is supplied with a dilution buffer for applications requiring lower concentrations of enzyme. |
优点: |
▪ Hydrolyzes the N-glycosidic bond between the deoxyribose sugar and uracil in DNA containing deoxyuridine in place of thymidine▪ Well-suited for use in DNA repair research studie |
相关产品: |
▪2´-Fluorine-dUTP(#R2F110U) |
参考文献: |
1. Lindahl, T. et al., (1977) J. Biol. Chem. 252, 3286. 2. Longo, M.C. et al., (1990) Gene 93, 125. |
技术参数 产品优点 - Hydrolyzes the N-glycosidic bond between the deoxyribose sugar and uracil in DNA containing deoxyuridine in place of thymidine
- Well-suited for use in DNA repair research studie
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