PDX1 Monoclonal Antibody (5A5)
货号:MA5-17148
规格:100 µg
价格:4805
产品类型:流式抗体
品牌:eBioscience
物种:人
宿主:小鼠
抗体亚型:IgG
荧光染料:Purified
类型: | 单抗 | 同型对照: | |
浓度: | 1 mg/mL | 用法: | 1:500-1:2000 (WB) ;1:200-1:400 (Flow) |
免疫原性: | Purified recombinant fragment of human PDX1 expressed in E. Coli. |
产品详细信息MA5-17148 targets PDX1 in FACS, pep-ELISA, and WB applications and shows reactivity with Human samples.The MA5-17148 immunogen is purified recombinant fragment of human PDX1 expressed in E. Coli.MA5-17148 detects PDX1 which has a predicted molecular weight of approximately 30.8kDa.靶标信息The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
数据 |
PDX1 Antibody (MA5-17148) in Flow Flow cytometric analysis of Jurkat cells using PDX1 monoclonal antibody (Product # MA5-17148) (green) and negative control (red). PDX1 Antibody (MA5-17148) in WB Western blot analysis of PDX1 using PDX1 monoclonal antibody (Product # MA5-17148) in HEK293 (1) and PDX1 (AA: 39-283) human IgG Fc transfected HEK293 (2) cell lysate. |
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二抗荧光二抗免疫组化一抗标签抗体 |
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