PDX1 Recombinant Rabbit Monoclonal Antibody (JM62-45)
货号:MA5-32790
规格:100 µL
价格:4732
产品类型:免疫组化一抗
品牌:eBioscience
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:Purified
类型: | 单抗 | 同型对照: | |
浓度: | 1 mg/mL | 用法: | 1:50-1:200 (ICC);1:50-1:200 (IF);1:50-1:200(IHC);1:500 (WB) |
免疫原性: | Synthetic peptide within C-terminal human PDX |
产品详细信息Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. 靶标信息PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in its gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
数据 |
PDX1 Antibody (MA5-32790) in IHC (P) Immunohistochemical analysis of PDX1 of paraffin-embedded Human pancreas tissue using a PDX1 Monoclonal antibody (Product #MA5-32790). The nuclear counter stain is DAPI (blue). PDX1 Antibody (MA5-32790) in IHC (P) Immunohistochemical analysis of PDX1 of paraffin-embedded Human pancreas tissue using a PDX1 Monoclonal antibody (Product #MA5-32790). Counter stained with hematoxylin. |
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二抗荧光二抗免疫组化一抗标签抗体 |
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