AFP Polyclonal Antibody

admin 2024-10-17 14

AFP Polyclonal Antibody

货号:PA5-16801

规格:500 µL

价格:0

产品类型:免疫组化一抗

品牌:eBioscience

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

类型:

多抗

同型对照:

浓度:

用法:

1:200(IHC (P));1:25 (WB)

免疫原性:

Human alpha-fetoprotein purified from human cord serum
产品详细信息PA5-16801 targets Alpha Fetoprotein in IHC (P) and WB applications and shows reactivity with Human samples.The PA5-16801 immunogen is human alpha-fetoprotein purified from human cord serum.靶标信息AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.

数据

AFP Antibody (PA5-16801) in IHC Formalin-fixed, paraffin-embedded human fetal liver stained with AFP using peroxidase-conjugate and AEC. Note cytoplasmic staining of fetal hepatocytes.

AFP Antibody (PA5-16801) in WB Western blot of Alpha Fetoprotein using Alpha Fetoprotein Polyclonal Antibody (Product # PA5-16801) on HEP-G-2 Cells.
二抗荧光二抗免疫组化一抗标签抗体
参考文献:

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