Matrigel Basement Membrane Matrix, Phenol Red-Free, *LDEV-Free
货号:356237
规格:10mL
价格:3332
产品类型:基础细胞培养和血清
品牌:Corning
Matrigel Matrix Phenol Red-free, *LDEV-free, 10 mL, is recommended for assays that require color detection (e.g. fluorescence). Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparin sulfate proteoglycans, entactin/nidogen, and a number of growth factors.Quality :Mouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testingExtensive PCR testing is performed to screen for a number of pathogensTested and found negative for bacteria, fungi, and mycoplasmaProtein concentrations determined by Lowry methodEndotoxin units measured by Limulus Amoebocyte Lysate assayMatrigel Matrix gel stability is tested for a period of 14 days at 37°C肝细胞通常用于基础科研与药物代谢等研究,新鲜和冻存的原代肝细胞都能够维持主要的药物和异物代谢的酶途径。肝细胞能够在I型胶原、Matrigel基质或PuraMatrix上生长并维持生物活性。Biocoat 肝细胞分化系统用于肝细胞相关研究,有以下特点:- 无血清条件下,持续培养肝细胞而细胞功能不丢失- 构建多用途的肝细胞体外模型- 至少维持3细胞色素P450(CYP1A1)的体外表达- 修复C/EBPα瞬时生长形态和极性- 维持肝细胞的活性,至少3周以上- 与I型胶原一起培养,对肝功能的研究时间可增长两倍BiocoatTM肝细胞分化系统可应用:- 基因表达的调控机制(如细胞色素P450)- 白蛋白表达- 胞外基质对肝脏基因和转录因子的调控- 代谢途径,包括药物代谢- 天然化合物和药物的转运系统- 药物对肝脏的毒性- 疾病引起的肝功能变异或受损 |
技术参数 产品应用 - Cell Growth and Differentiation - Metabolism/Toxicology Studies - Invasion Assays - in vitro and in vivo Angiogenesis Assays - in vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice
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