PuraMatrix Peptide Hydrogel PuraMatrix肽段水凝胶
货号：354250
规格：5mL
价格：4029
产品类型：神经细胞培养
品牌：Corning
| PuraMatrix Peptide Hydrogel is a synthetic matrix used to create defined three dimensional (3D) micro-environments for a variety of cell culture experiments. To achieve optimal cell growth and differentiation, it is necessary to determine the appropriate mixture of this material and bioactive molecules (e.g., growth factors, extracellular matrix (ECM) proteins, and/or other molecules). Corning PuraMatrix Peptide Hydrogel consists of standard amino acids (1% w/v) and 99% water. Under physiological conditions, the peptide component self-assembles into a 3D hydrogel with a nanometer-scale fibrous structure. The hydrogel is readily formed in a Falcon culture dish, plate, or cell culture insert.Corning PuraMatrix Peptide Hydrogel has been shown to promote differentiation of hepatocyte progenitor cells, rat pheochromocytoma cells (PC12), hippocampal neurons, and endothelial cells. Studies have also demonstrated the hydrogel supports the attachment of a variety of primary (e.g., neuronal, fibroblast, keratinocyte) and transformed (e.g., MG-63, SH-SY5Y, HEK293, NIH3T3) cell types. Other potential applications include stem cell proliferation, tumor cell migration and invasion, angiogenesis assays, and in vivo analyses of tissue regeneration.Quality• Tested and found negative for bacteria, fungi, and mycoplasma• Cell viability = 80% based on cytotoxicity analysis of NIH3T3 fibroblasts• Identity confirmed using mass spectrometry• Demonstration of fiber formation using a self-assembly assay 康宁PuraMatrix 肽段水凝胶是人工合成的基质，可以为各种类型细胞的培养提供三维空间的微环境。它由1%的氨基酸和99%的水组成，可自组装形成纳米级的纤维状结构（平均孔径为50-200 nm）。康宁PuraMatrix 肽段水凝胶可促进多种细胞（如肝前体细胞，大鼠PC12细胞，海马神经元和内皮细胞等）的分化，原代细胞（如神经元，成纤维细胞和角质细胞等）和转染细胞系（如MG-63,SH-SY5Y,HEK-293,NIH3T3等）的贴壁。另外，康宁PuraMatrix 肽段水凝胶还可用于干细胞的增殖，肿瘤细胞的迁移与侵袭，血管生成及组织再生的体内分析。来源：人工合成。4-30℃下保存。 |
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