Pierce Premium Grade SPDP 交联剂
货号:PG82087,PG82088
规格:100 mg,1 g
价格:5678,0
产品类型:蛋白表达研究
品牌:Thermo Fisher
| Thermo Scientific Pierce Premium Grade SPDP is our highest quality formulation of this pyridyldithiol-based amine-to-sulfhydryl crosslinker, specially characterized for applications where product integrity and risk minimization are paramount. SPDP is a disulfide crosslinker used for reversible (reducible) amine-to-sulfhydryl conjugation.Compared to the standard grade product, Premium Grade SPDP provides more clearly defined quality and product support by including increased analytical testing and product characterization, greater batch-specific information and quality assurance review, extensive lot sample retention, and change control notification.SPDP is N-succinimidyl 3-(2-pyridyldithio)-propionate, a crosslinker for amine-to-sulfhydryl conjugation that forms cleavable (reducible) disulfide bonds with cysteine sulfhydryls. At one end is an N-hydroxysuccinimide (NHS) ester that will react with a primary amine to form a stable amide bond. At the other end is a pyridyl disulfide group that will react with a sulfhydryl group to form a reversible disulfide bond. |
| 特点: |
| - High quality—identity and purity confirmed by multiple tests, including quantitative NMR- Product integrity—enhanced level of testing and characterization compared to standard grade- Lot retention—ample supply of past lots retained to help ensure future process testing- Change management—Change Control Notification (CCN) service- Consistent manufacture—batch-specific manufacturing documentation review |
| 数据: |
Chemical structure of SPDP crosslinking reagentA disulfide crosslinker for reversible (reducible) amine-to-sulfhydryl conjugation |