2'-O-Methyl-C(Bz)-Suc-CPG; 500 Å (RNA)
货号:BG5-1100MR-1
规格:1 g
价格:3940
产品类型:核酸合成
品牌:LGC Biosearch Technologies
| 2’-O-Methyl-C(Bz)-Suc-CPG is used for synthesis of oligonucleotides that contain nuclease resistant 2’-O-methyl linkages to prevent degradation. The 2’-O-Methyl-C(Bz)-Suc-CPG requires no special handling or deprotection reagents. The 500 Å CPG is best suited for the synthesis of RNA sequences up to 50-mers in length. |
| 特性: |
| - Appearance: white powder |
| 产品用途: |
| - Synthesis conditions: Follow the instrument manufacturer's protocol when using this product.- Cleavage conditions: Use concentrated ammonia for 90 minutes at 25°C or for 30 minutes at 60°C. When using fast deprotecting amidites( CAc; GDMF) 1:1 ammonia:methylamine (AMA) for 25 minutes at 25°C may also be used.- Deprotection conditions:When using fast deprotecting amidites (eg. C-Ac, G-DMF) use concentrated ammonia for 1 hour or AMA for 30 minutes at 60 °C. When using standard amidites (eg. C-Bz, G-iBu) use concentrated ammonia for 5 hours at 60 °C.
This RNA support is compatible with deprotection chemistries used with 2’ Fluoro; 2' modified phosphoramidites and TBDMS protected reagents.- The mass this product adds after conjugation and work-up (the additional mass seen by mass spectrometry) is:319.21 |
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