| Stellaris FISH Probes, Human ESR1 with Quasar 670 Dye consists of a set of dye-labeled oligos mixed and pooled into a final delivered amount of 5 nmol, which yields approximately 200-400 hybridizations under standard conditions. Designed to detect ESR1 transcripts in specimens using fluorescence in situ hybridization (FISH).
Design Criteria: Product was designed against estrogen receptor 1 ESR1 a.k.a. ER; ESR; Era; ESRA; ESTRR; NR3A1 (NCBI gene ID:2099) and nucleotides 687-877, 878-994, 995-1330, 1331-1469, 1470-1603 of NM_000125.3. This is an inclusive and exclusive probe set designed to also detect the following variants: NM_001122740, NM_001122741, NM_001291230, XM_006715374, XM_006715375, ENST00000338799, ENST00000427531, and ENST00000440973, and partially: ENST00000206249 (exons 14 and 15a), ENST00000406599, (exon 15a), ENST00000415488 (exons 10, 14, 15b), ENST00000443427 (exons 9, 10, 14, 15a), ENST00000456483 (exons 9, 10, 14, 15a), and ENST00000482101 (exon 11), but NOT: ENST00000404742, ENST00000446550, ENST00000473497, or ENST00000488573. Note: Avoids similar sequence to ESR2, ESRRA, ESRRB, and ESRRG within second common exon. The probe set has not been tested for potential cross-hybridization to RNA(s) of paralogous and orthologous gene(s) in the same or other species. |
QQ:1749072012