FSTL3/FLRG Human ELISA Kit/人FSTL3/FLRG ELISA试剂盒
货号：EHFSTL3,EHFSTL3X5,EHFSTL3X10
规格：96 tests,5X96 tests,10X96 tests
价格：7238,29891,52892
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 250 pg/mL |
| 检测范围 | 204.8-50,000 pg/mL |
样本类型/体积 | 上清液 100 μL 血清 50 μL 血浆 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 分析稀释浓缩液 - 生物素化检测抗体 -SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | FSTL3 |
| Protein aliases | follistatin-like 3 (secreted glycoprotein), Follistatin-like protein 3, Follistatin-related gene protein, Follistatin-related protein 3 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | FLRG, FSRP, FSTL3, UNQ674/PRO1308 |
| Gene ID | (Human) 10272 |
| Gene symbol | FSTL3 |
| UniProt ID | (Human) O95633 |
| The Human FSTL3/FLRG (Hu FLRG) ELISA quantitates Hu FLRG in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu FLRG.人FSTL3 / FLRG（Hu FLRG）ELISA定量了人血清，血浆或细胞培养基中的人FLRG。 该检测试剂盒将专门识别天然和重组人FLRG。Principle of the method 方法原理The Human FLRG solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.人FLRG固相夹心ELISA（酶联免疫吸附测定）设计用于测量匹配的抗体对之间结合的靶标量。 已在提供的微孔板的孔中预包被了靶标特异性抗体。 然后将样品，标准液或质控品添加到这些孔中，并与固定的（捕获）抗体结合。 通过添加第二（检测器）抗体形成三明治，添加底物溶液，该底物溶液与酶-抗体-靶标复合物反应以产生可测量的信号。 该信号的强度与原始样品中存在的靶标浓度成正比。Rigorous validation 严格验证Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.此ELISA试剂盒的每个制造批次均经过质量测试，其标准包括敏感性，特异性，精密度和批次间一致性。 有关验证的更多信息，请参见手册。Target information 靶标信息Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.同工型1或分泌型是TGF-β家族成员（例如激活素，BMP2和MSTN）的结合和拮抗蛋白。 抑制激活素A，激活素B，BMP2和MSDT诱导的细胞信号转导； 参与骨形成；对激活素A比对激活素B更有效。 抑制破骨细胞分化 参与造血； 参与造血祖细胞的分化，增加造血细胞对纤连蛋白的粘附，似乎有助于造血前体细胞与骨髓基质的粘附。 亚型2或核形式可能通过与MLLT10相互作用而参与转录调控。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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