Uromodulin (UMOD) Human ELISA Kit/人Uromodulin (UMOD) ELISA试剂盒
货号：EHUMOD,EHUMODX5,EHUMODX10
规格：96 tests,5X96 tests,10X96 tests
价格：7238,29826,52892
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 40 pg/mL |
| 检测范围 | 40.96-10,000 pg/mL |
样本类型/体积 | 上清液 100 μL 血清 1 μL 血浆 1 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 分析稀释浓缩液 - 生物素化检测抗体 -SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | Uromodulin |
| Protein aliases | Tamm-Horsfall urinary glycoprotein, THP, Uromodulin, secreted form, uromucoid |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP, UMOD |
| Gene ID | (Human) 7369 |
| Gene symbol | UMOD |
| UniProt ID | (Human) P07911 |
| The Human Uromodulin (UMOD) ELISA quantitates Hu UMOD in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu UMOD.人尿调蛋白（UMOD）ELISA可以定量人血清，血浆或细胞培养基中的人UMOD。 该检测试剂盒将专门识别天然和重组人UMOD。Principle of the method 方法原理The Human UMOD solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.人UMOD固相夹心ELISA（酶联免疫吸附测定）设计用于测量匹配的抗体对之间结合的靶标量。 已在提供的微孔板的孔中预包被了靶标特异性抗体。 然后将样品，标准液或质控品添加到这些孔中，并与固定的（捕获）抗体结合。 通过添加第二（检测）抗体形成三明治，添加底物溶液，该底物溶液与酶-抗体-靶标复合物反应以产生可测量的信号。 该信号的强度与原始样品中存在的靶标浓度成正比。Rigorous validation 严格验证Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.此ELISA试剂盒的每个制造批次均经过质量测试，其标准包括敏感性，特异性，精密度和批次间一致性。 有关验证的更多信息，请参见手册。Target information 靶标信息This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.该基因编码尿调节蛋白，是正常尿液中最丰富的蛋白质。 它在尿液中的排泄是由于其糖基磷脂酰肌醇锚定的对应物的胞外域的蛋白水解切割，该对应物位于亨利环的腔细胞表面。 尿调节蛋白可以充当肾液中钙结晶的组成性抑制剂。 尿液中尿调节素的排泄可以防御由尿路致病菌引起的尿路感染。 该基因的缺陷与常染色体显性肾脏疾病，髓样囊性肾病2（MCKD2）和家族性青少年高尿酸血症性肾病（FJHN）有关。 这些疾病的特征是青少年高尿酸血症，痛风和进行性肾衰竭。 尽管该基因可能存在几种转录物变体，但迄今为止仅描述了两种的全长性质。 这两个代表该基因的主要变体，并编码相同的同工型。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-20639.htm
QQ:1749072012