GAS6 Mouse ELISA Kit/小鼠GAS6 ELISA试剂盒
货号：EMGAS6,EMGAS6X5,EMGAS6X10
规格：96 tests,5X96 tests,10X96 tests
价格：7238,29891,52892
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：小鼠
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 20 pg/mL |
| 检测范围 | 20.48-5000 pg/mL |
样本类型/体积 | 上清液 100 μL 血清 10 μL 血浆 10 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 分析稀释浓缩液 - 生物素化检测抗体 -SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | GAS6 |
| Protein aliases | AXL receptor tyrosine kinase ligand, GAS 6, GAS-6, Growth arrest-specific protein 6 |
物种（Tested） | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | Gas-6, Gas6 |
| Gene ID | (Mouse) 14456 |
| Gene symbol | Gas6 |
| UniProt ID | (Mouse) Q61592 |
| The Mouse GAS6 ELISA quantitates Ms GAS6 in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms GAS6.小鼠GAS6 ELISA定量检测小鼠血清，血浆或细胞培养基中的GAS6。 该检测试剂盒将专门识别天然和重组Ms GAS6。Principle of the method 方法原理The Mouse GAS6 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.小鼠GAS6固相夹心ELISA（酶联免疫吸附测定）是测量匹配的抗体对之间结合的靶标量。 已在孔中预包被了靶标特异性抗体。 然后将样品，标准液或质控品添加到这些孔中，并与固定的（捕获）抗体结合。 通过添加第二（检测）抗体形成三明治，添加底物溶液，该底物溶液与酶-抗体-靶标复合物反应以产生可测量的信号。 该信号的强度与原始样品中存在的靶标浓度成正比。Rigorous validation 严格验证Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.此ELISA试剂盒的每个制造批次均经过质量测试，其标准包括敏感性，特异性，精密度和批次间一致性。 有关验证的更多信息，请参见手册。Target information 靶标信息Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.生长停滞的特定蛋白质，包括Gas1和Gas6，在静态细胞中被激活。 Gas1诱导的生长停滞由p53介导，并且Gas1似乎能够抑制肿瘤细胞的生长。 Gas6是酪氨酸激酶受体Axl的配体，最初被确定为维生素K依赖性蛋白家族的成员，并且与蛋白S（凝结途径中的负协同调节剂）表现出高度的氨基酸序列同源性。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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