CD9 Monoclonal Antibody (5G6)/CD9 单抗 (5G6)
货号:MA5-17049
规格:100 µL
价格:4805
产品类型:免疫组化一抗
品牌:Thermo Fisher
抗原:Synthesized peptide of human CD9.
物种:人/小鼠
宿主:小鼠
抗体亚型:其它
克隆号:5G6
荧光染料:其它
类型: | 单抗 | 同型对照: | IgG1 |
浓度: | | 用法: | 1:200 - 1:400(Flow);1:200 - 1:1000(IHC);1:500 - 1:2000(WB) |
产品详细信息MA5-17049 targets CD9 in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human samples.The MA5-17049 immunogen is synthesized peptide of human CD9.MA5-17049 detects CD9 which has a predicted molecular weight of approximately 25kDa.靶标信息CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
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参考文献: |
1.PloS one Death of Monocytes through Oxidative Burst of Macrophages and Neutrophils: Killing in Trans. 2.Nature Cell diversity and network dynamics in photosensitive human brain organoids. 3.PLoS genetics Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS. 4.Scientific reports Mammalian TRAPPIII Complex positively modulates the recruitment of Sec13/31 onto COPII vesicles. 5.Scientific reports Progressive Muscle Cell Delivery as a Solution for Volumetric Muscle Defect Repair. |
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