CD9 Polyclonal Antibody/CD9多抗

货号：PA5-86534

规格：100 µL

价格：4732

产品类型：免疫组化一抗

品牌：Thermo Fisher

抗原：Synthetic peptide, corresponding to amino acids 10

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	多抗	同型对照：	IgG
浓度：	1 mg/mL	用法：	1:50-1:200(IHC (P));1:500-1:1000(WB)

靶标信息CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.

数据

CD9 Antibody (PA5-86534) in WBWestern blot analysis of CD9 in Lane 1: THP-1 whole cell lysate (40 µg), Lane 2: Peripheral blood cells tissue lysate of rat (30 µg), Lane 3: Peripheral blood cells tissue lysate of mouse (30 µg). Sample was incubated with CD9 polyclonal antibody (Product # PA5-86534) using a 1:500 dilution.

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技术参数

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