CD9 Monoclonal Antibody (MEM-61)/CD9 单抗 (MEM-61)
货号：MA1-19002
规格：100 µg
价格：4880
产品类型：免疫组化一抗
品牌：Thermo Fisher
抗原：Pre-B cell line NALM-6.
物种：人
宿主：小鼠
抗体亚型：其它
克隆号：MEM-61
荧光染料：其它
| 类型: | 单抗 | 同型对照： | IgG1 |
| 浓度： | 1 mg/mL | 用法： | 5 µg/mL(Flow);20 µg/mL(IHC);2-4 µg/mL(WB) |
产品详细信息This antibody recognizes an epitope on second extracellular domain (EC2) of CD9 antigen. It has also been sucessfully used in Mass Cytometry (CyTof).靶标信息CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
QQ:1749072012