IL-5 Monoclonal Antibody (TRFK5)/IL-5单克隆抗体（TRFK5）

货号：BMS179

规格：100μg

价格：2855

产品类型：流式抗体

品牌：eBioscience

物种：小鼠

宿主：大鼠

抗体亚型：IgG

克隆号：TRFK5

荧光染料：其它

类型:	单抗	同型对照：
浓度：	1 mg/mL1 mg/mL	用法：	Assay-Dependent(ELISA)；Assay-Dependent(Flow)B)

产品详细信息Description: The TRFK5 antibody reacts with mouse interleukin-5 (IL-5) and cross-reacts with human IL-5. The TRFK5 antibody has been reported to cross react with IL-5 from rhesus monkey.Applications Tested: ELISA, Flow Cytometry (Intracellular Staining).靶标信息IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

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参考文献：

1.Nature immunologyOX40 signaling favors the induction of T(H)9 cells and airway inflammation."BMS179 was used in Flow cytometry/Cell sorting to identify a previously unknown mechanism for the induction of Th9 cells, with potential clinical implications in allergic inflammation."AuthorsXiao X,Balasubramanian S,Liu W,Chu X,Wang H,Taparowsky EJ,Fu YX,Choi Y,Walsh MC,Li XC

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