Human IL-13 Recombinant Protein, eBioscience/人IL-13重组蛋白
货号:BMS351
规格:10 µg
价格:5591
产品类型:蛋白表达研究
品牌:eBioscience
产品详细信息Description: Interleukin-13 is an immunoregulatory protein produced by activated T-lymphocytes. The biological activities of IL-13 include the stimulation of B cell proliferation and immunoglobulins production. Recombinant human IL-13 is a 12.5 kDa protein containing 114 amino acid residues.Purity: >95%.Molecular Weight: 12.5 kDa.靶标信息IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
技术参数 产品应用 (Ctrl)Assay-Dependent