HIST1H2AG Polyclonal Antibody/HIST1H2AG多克隆抗体
货号:PA5-24822
规格:400 µL
价格:4880
产品类型:抗体和染料
品牌:Thermo Fisher
抗原:KLH conjugated synthetic peptide between 103-130 a
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:其它
| 类型: | 多抗 | 同型对照: | |
| 浓度: | Lot-specific | 用法: | 1.5 µg/1x10^6 cells(ChIP);1:10-1:50(Flow);1:100(ICC);1:100(IF);1:50-1:100(IHC (P));1:1000(WB) |
产品详细信息This antibody is predicted to react with bovine, mouse and rat based on sequence homology.靶标信息Histones are nuclear proteins that play an important role in maintaining the structure of the chromosome in eukaryotes. The nucleosome is made up of around 146bp of DNA, which enfolds around a histone octomer unit comprising of four major histones, H2A, H2B, H3 and H4. An important role of H2A is to ensure proper assembly or functioning of the centrometre. They also play an important role in gene regulation. The protein can be modified by acetylation and phosphorylation.
| 数据: |
HIST1H2AG Antibody (PA5-24822)Antibody specificity was demonstrated by detection of enrichment of the target protein at specific gene loci. Chromatin Immunoprecipitation (ChIP) was performed using Anti-HIST1H2AG Polyclonal Antibody (Product # PA5-24822) with relevant positive (c-Fos, ALDOA, GAPDH) and negative (MYOD, SAT2 satellite repeats, SAT Alpha) target genes/ binding sites. HIST1H2AG Antibody (PA5-24822) in FlowFlow cytometry analysis of HepG2 cells using a HIST1H2AL polyclonal antibody (Product # PA5-24822) (right) compared to a negative control cell (left) at a dilution of 1:10-50, followed by a FITC-conjugated goat anti-rabbit antibody |
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