p300 Monoclonal Antibody (RW109)/p300单克隆抗体（RW109）
货号：MA1-16623
规格：200 µL
价格：5548
产品类型：抗体和染料
品牌：Thermo Fisher
抗原：Fusion protein containing residues 1572-2371 of hu
物种：其它
宿主：小鼠
抗体亚型：IgG1, kappa
克隆号：RW109
荧光染料：其它
| 类型: | 单抗 | 同型对照： | |
| 浓度： | Conc. Not Determined | 用法： | Assay-Dependent(ChIP)；1:100-1:200(ICC)；1:100-1:200(IF)；1:10-1:500(IP)；1:1000(WB) |
产品详细信息Suggested positive control: HeLa nuclear extract.靶标信息EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
| 数据： |
p300 Antibody (MA1-16623) in WBp300 detected in a HeLa nuclear extract using 1 (1:1,000). ECL: 20 minute exposure. |
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