SARS-CoV/SARS-CoV-2 Spike Protein (S-RBD) Chimeric Recombinant Mouse Monoclonal Antibody (D005)

货号：MA5-35958

规格：100μl

价格：7640

产品类型：抗体和染料

品牌：Thermo Fisher

物种：其它

宿主：小鼠

抗体亚型：IgG1, kappa

荧光染料：其它

类型:	单抗	同型对照：
浓度：	1 mg/mL	用法：	1:5,000-1:10,000(ELISA)

产品详细信息This product is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified, recombinant SARS-CoV Spike RBD Protein. The antibody was produced using recombinant antibody technology.靶标信息It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.

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