Human Dectin-1 ELISA Kit/人Dectin-1 ELISA试剂盒
货号：EH150RB,EH150RBX5
规格：96 tests,5X96 tests
价格：6641,29884
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.082 ng/mL |
| 检测范围 | 20-0.082 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | Dectin 1 (Clec7a) |
| Protein aliases | Beta-glucan receptor, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, CD369, DC-associated C-type lectin 1, dectin-1, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, lectin-like receptor 1 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | BGR, CANDF4, CD369, CLEC7A, CLECSF12, DECTIN1, SCARE2, UNQ539/PRO1082 |
| Gene ID | (Human) 64581 |
| Gene symbol | CLEC7A |
| UniProt ID | (Human) Q9BXN2 |
| Human Dectin-1 Kit quantitates human Dectin-1 Kit in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Dectin-1 Kit.人Dectin-1定量分析血清，血浆，上清液中的人Dectin-1。 该检测试剂盒将专门识别天然和重组人Dectin-1。Target informationCLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.CLEC7A，也称为dectin-1，是C型凝集素/ C型凝集素样结构域（CTL / CTLD）超家族的成员，主要在髓样细胞上表达。 它是具有细胞外C型凝集素样结构域折叠和带有基于免疫受体酪氨酸的激活基序（ITAM）的细胞质结构域的小型II型糖蛋白膜受体。 CLEC7A充当模式识别受体，可识别来自真菌和植物的多种β-1,3-连接的和β-1,6-连接的葡聚糖，并以此方式在先天免疫应答中发挥作用。 真菌接触后，CLEC7A激活Syk酪氨酸激酶，通过形成活性氧而触发大规模的氧化爆发。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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