Human Desmoglein-3 ELISA Kit/人Desmoglein-3 ELISA试剂盒
货号:EH155RB,EH155RBX5,EH155RBX10
规格:96 tests,5X96 tests,10X96 tests
价格:6641,29884,57271
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:人
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 34 pg/mL |
检测范围 | 34-8,000 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | Desmoglein 3 |
Protein aliases | 130 kDa pemphigus vulgaris antigen, Cadherin family member 6, Desmoglein-3, PVA |
物种(Tested) | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | CDHF6, DSG3, PVA |
Gene ID | (Human) 1830 |
Gene symbol | DSG3 |
UniProt ID | (Human) P32926 |
Human Desmoglein-3 quantitates human Desmoglein-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Desmoglein-3.人Desmoglein-3定量测定血清,血浆,上清液中的人Desmoglein-3。 该检测试剂盒将专门识别天然和重组人Desmoglein-3。Target information 靶标信息Desmoglein 3 (Dsg3), also known as Cadherin family member 6 (CDHF6), is a member of the desmosomal cadherin family and plays a critical role in cell-cell adhesion. It is predominately expressed in stratified squamous epithelium, including the skin, oral mucosa, and esophagus. Desmoglein 3 has been characterized as the auto-antigen of pemphigus vulgaris (PV), a life-threatening autoimmune disease. Binding of anti-Desmoglein 3 autoantibodies causes the loss of cell-cell adhesion, which clinically manifests as blisters on the skin and oral mucosa, and histologically as suprabasilar acantholysis.Desmoglein 3(Dsg3),也称为Cadherin家族成员6(CDHF6),是desmosomal cadherin家族的成员,并且在细胞间粘附中起关键作用。 它主要在分层的鳞状上皮中表达,包括皮肤,口腔粘膜和食道。 Desmoglein 3被表征为寻常型天疱疮(PV)的自身抗原,一种威胁生命的自身免疫性疾病。 抗桥粒芯糖蛋白3自身抗体的结合会导致细胞间粘附的丧失,临床上表现为皮肤和口腔粘膜上的水泡,组织学上表现为睑上腺棘皮松解术。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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