TIP60 Polyclonal Antibody

货号：PA5-23290

规格：100 µg

价格：5548

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Synthetic peptide (499 CLHFTPKDWSKRGK 512) of TIP6

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.5 mg/mL	用法：	5 µg/mL(IHC(P));0.25-1 µg/mL(WB)

靶标信息TIP60 is a transcription factor, originally isolated as an HIV-1 TAT-interactive protein, known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and targets it for degradation. It belongs to the MYST family of histone acetyl transferases (HATs). TIP60 is a catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. A co-regulator of transcription factors, TIP60 either promotes or suppresses tumorigenesis. TIP60 is an enzyme that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.

数据：

TIP60 Antibody (PA5-23290) in IHC (P)Immunohistochemical analysis of TIP60 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top) and a TIP60 polyclonal antibody (Product # PA5-23290) (bottom) at5 µg/mL. TIP60 Antibody (PA5-23290) in WBWestern blot analysis of TIP60 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain and 4) rat brain lysate using a TIP60 polyclonal antibody (Product # PA5-23290) at 0.25 µg/mL.

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