KMT2C Polyclonal Antibody

货号：PA5-67359

规格：100 µL

价格：6049

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant Human KMT2C

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.2 mg/mL	用法：	0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF)

产品详细信息Immunogen sequence: TPPTMSQPTFP MVPQQLQHQQ HTTVISGHTS PVRMPSLPGW QPNSAPAHLP LNPPRIQPPI AQLPIKTCTP APGTVSNANP QHighest antigen sequence identity to the following orthologs - mouse 88%, rat 33%. 靶标信息Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

数据：

KMT2C Antibody (PA5-67359) in IFImmunofluorescent staining of KMT2C in human cell line U-2 OS shows localization to nucleoplasm. Samples were probed using a KMT2C Polyclonal Antibody (Product # PA5-67359).

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