Human AMICA ELISA Kit/人AMICA ELISA试剂盒
货号：EH22RB,EH22RBX5,EH22RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.41 ng/mL |
| 检测范围 | 0.41-100 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | AMICA |
| Protein aliases | adhesion molecule AMICA, Adhesion molecule interacting with CXADR antigen 1, adhesion molecule, interacts with CXADR antigen 1, Dendritic cell-specific protein CREA7-1, dendritic-cell specific protein CREA7-1, dendritic-cell specific protein CREA7-4, Junctional adhesion molecule-like |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | AMICA, AMICA1, CREA7-1, CREA7-4, Gm638, JAML, UNQ722/PRO1387 |
| Gene ID | (Human) 120425 |
| Gene symbol | JAML |
| UniProt ID | (Human) Q86YT9 |
| Human AMICA quantitates human AMICA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human AMICA.人AMICA定量测定血清，血浆，上清液中的人AMICA。该检测试剂盒将专门识别天然和重组人AMICA。Target information 靶标信息AMICA transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.白细胞质膜的AMICA跨膜蛋白，可通过与CXADR相互作用来控制其迁移和激活，CXADR是在邻近的上皮和内皮细胞上发现的质膜受体。两种受体之间的相互作用介导了γ-δT细胞的活化，γ-T细胞是驻留在上皮细胞中并参与组织稳态和修复的T细胞亚群。在上皮CXADR结合后，JAML通过PI3激酶和MAP激酶在γ-δT细胞中诱导下游细胞信号转导事件。它导致T细胞增殖，产生细胞因子和生长因子，进而刺激上皮组织修复。它还通过与上皮和内皮CXADR的粘着相互作用来控制白细胞在上皮和内皮组织内的迁移。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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