EHMT1 Polyclonal Antibody

货号：PA5-111499

规格：100 µL

价格：6301

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant Protein corresonding to Human EHMT1

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：		用法：	0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF)

产品详细信息Immunogen sequence: ADGETNGSCE NSDASSHANA AKHTQDSARV NPQDGTNTLT RIAENGVSER DSEAAKQNHV TADDFVQTSV IGSNGYILNK PALQAQPLRT TSTLASSLPG HAAKTLPGGA GKGRTPSAFP QTPAAPPATL 靶标信息EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

数据：

EHMT1 Antibody (PA5-111499) in ICCImmunofluorescent staining of EHMT1 in human cell line MCF7 using EHMT1 Polyclonal Antibody (Product # PA5-111499) shows localization to nucleoplasm and nuclear bodies.

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